Genotoxic stress leads to DNA damage which can be detrimental to the cell. A well‐orchestrated cellular response is mounted to manage and repair the genotoxic stress‐induced DNA damage. Our understanding of genotoxic stress response is derived mainly from studies focused on transcription, mRNA splicing, and protein turnover. Surprisingly not as much is understood about the role of mRNA translation and decay in genotoxic stress response. This is despite the fact that regulation of gene expression at the level of mRNA translation (...) and decay plays a critical role in a myriad of cellular processes. This review aims to summarize some of the known findings of the role of mRNA translation and decay by focusing on two categories of examples. We discuss examples of mRNA whose fates are regulated in the cytoplasm and RNA‐binding proteins that regulate mRNA fates in response to genotoxic stress. (shrink)

Издание содержит: Музыка моя; XIX век. Россия. первые опыты философствования о музыке; XIX век. Россия. Четыре имени в метафизике музыки; XX век. Мордовия. Бахтинские и яушевские страницы и др.

In rhetoric, an orator needs both a large vocabulary and a stock of commonplaces and arguments. Erasmus put them together in his De duplici copia verborum ac rerum . In this sixth volume of the first Ordo of the Amsterdam edition of the Latin texts of Erasmus, Betty Knott has edited the Latin text and added an English introduction and commentary, providing philological and historical information which helps the reader to understand the text and identify its sources.

Ghazzālī, 1058-1111; Kīmiyā-yi saʻādat -Criticism and interpretation ; Ghazzālī, Aḥmad ibn Muḥammad, -1126; Savāniḥ -Criticism and interpretation ; Ghazzālī, Aḥmad ibn Muḥammad, -1126; Baḥr al-muḥabbat fī asrār al-muvaddat fītafsīr Sūrah-i Yūsuf -Criticism.

On essence of Mādhyamika philosophy by Lcaṅ-skya II Rol-paʼi-rdo-rje, 1717-1786 and commentaries by Dkon-mchog-ʼjigs-med-dbang-po, Khri-chen-bstan-pa-rab-rgya, and Dalai Lama XIV Bstan-ʼdzin-rgya-mtsho, 1935-.

Collected works of Rol-paʼi-rdo-rje on the doctrines of Dge-lugs-pa (Sect) and Buddhist philosophy.

Вниманию читателя предлагаются статьи, посвященные мало исследованным проблемам логики (и психологии) художественного творчества, в частности в работах М. Бахтина. Книга содержит также хрестоматию "Искусство и логика" и предметный указатель.

The articles assembled in this volume present an important selection of Professor Jao Tsung-i’s research in the fields of comparative mythology, early Chinese hemerology and the interrelation between divination, morals and ritual in early Chinese thought.

Nikolai Zhinkin’s review of Ernst Cassirer is so far the earliest document of the discussion in Russia about Cassirer’s conception of myth and his theory of symbolic forms. The text is published from Zhinkin’s archive. Zhinkin here notes a reorientation of Neo-Kantianism that reveals its hidden relativism and stands as a symptom of its downfall.